Serum hormone concentrations were measured by electrochemiluminescence immunoassays.Īfter applying sampling weights and adjusting for age, percent body fat, alcohol, smoking, and activity, testosterone concentrations were not different between non-Hispanic blacks (n = 363 geometric mean, 5.29 ng/ml) and non-Hispanic whites (n = 674 5.11 ng/ml P > 0.05) but were higher in Mexican-Americans (n = 376 5.48 ng/ml P < 0.05). Our objective was to compare serum testosterone, estradiol, and SHBG concentrations among non-Hispanic black, non-Hispanic white, and Mexican-American men.Ī total of 1413 men aged 20+ yr and who attended the morning examination session of the Third National Health and Nutrition Examination Survey (NHANES III) in 1988-1991 were included in this cross-sectional study. Previous studies comparing hormone levels by race might have been limited by size, restricted age variation, or lack of representation of the general population. Higher testosterone in black compared with white men has been postulated to explain their higher prostate cancer incidence.
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